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In Vivo Inflammation Does Not Impair ABCA1-Mediated Cholesterol Efflux Capacity of HDL

HDL provides atheroprotection by facilitating cholesterol efflex from lipid-laden macrophages in the vessel wall. In vitro studies have suggested impaired efflux capacity of HDL following inflammatory changes. We assessed the impact of acute severe sepsis and mild chronic inflammatory disease on the...

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Detalles Bibliográficos
Autores principales: Franssen, Remco, Schimmel, Alinda W. M., van Leuven, Sander I., Wolfkamp, Simone C. S., Stroes, Erik S. G., Dallinga-Thie, Geesje M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348631/
https://www.ncbi.nlm.nih.gov/pubmed/22611487
http://dx.doi.org/10.1155/2012/610741

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