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Oxidation of Low-Density Lipoprotein by Iron at Lysosomal pH: Implications for Atherosclerosis
[Image: see text] Low-density lipoprotein (LDL) has recently been shown to be oxidized by iron within the lysosomes of macrophages, and this is a novel potential mechanism for LDL oxidation in atherosclerosis. Our aim was to characterize the chemical and physical changes induced in LDL by iron at ly...
Autores principales: | Satchell, Leanne, Leake, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2012
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348679/ https://www.ncbi.nlm.nih.gov/pubmed/22493939 http://dx.doi.org/10.1021/bi2017975 |
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