Electrochemical Direct Determination of Catecholamines for the Early Detection of Neurodegenerative Diseases

Smart (Nano) materials with biosensing functions posses enormous potential in development of new generation of stable biosensors, chemical sensors, and actuators. Recently, there is a considerable interest in using TiO(2) nanostructured materials as a film-forming material since they have high surface area, optical transparency, high bio-compatibility, and relatively good conductivity. In this work, TiO(2) nanostructured films were used as nanoporous electrodes to study the electron transfer mechanisms of dopamine. epinephrine and norepinephrine, in order to develop a new generation of chemical sensors. The interesting results obtained are described herein and the analytical characterization of these neurotransmitter sensors is reported.