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Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population

BACKGROUND: Acquired myasthenia gravis (MG) is a rare antibody-mediated autoimmune disease caused by impaired neuromuscular transmission, leading to abnormal muscle fatigability. The aetiology is complex, including genetic risk factors of the human leukocyte antigen (HLA) complex and unknown environ...

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Detalles Bibliográficos
Autores principales: Maniaol, Angelina H., Elsais, Ahmed, Lorentzen, Åslaug R., Owe, Jone F., Viken, Marte K., Sæther, Hanne, Flåm, Siri T., Bråthen, Geir, Kampman, Margitta T., Midgard, Rune, Christensen, Marte, Rognerud, Anna, Kerty, Emilia, Gilhus, Nils Erik, Tallaksen, Chantal M. E., Lie, Benedicte A., Harbo, Hanne F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348874/
https://www.ncbi.nlm.nih.gov/pubmed/22590574
http://dx.doi.org/10.1371/journal.pone.0036603