Muramyl Dipeptide Induces NOD2-Dependent Ly6C(high) Monocyte Recruitment to the Lungs and Protects Against Influenza Virus Infection

Bacterial peptidoglycan-derived muramyl dipeptide (MDP) and derivatives have long-recognized antiviral properties but their mechanism of action remains unclear. In recent years, the pattern-recognition receptor NOD2 has been shown to mediate innate responses to MDP. Here, we show that MDP treatment...

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Detalles Bibliográficos
Autores principales: Coulombe, François, Fiola, Stéphanie, Akira, Shizuo, Cormier, Yvon, Gosselin, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348889/
https://www.ncbi.nlm.nih.gov/pubmed/22590599
http://dx.doi.org/10.1371/journal.pone.0036734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348889/
https://www.ncbi.nlm.nih.gov/pubmed/22590599
http://dx.doi.org/10.1371/journal.pone.0036734

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