The HPV E6 oncoprotein targets histone methyltransferases for modulating specific gene transcription

Expression of viral proteins causes important epigenetic changes leading to abnormal cell growth. Whether viral proteins directly target histone methyltransferases (HMTs), a key family enzyme for epigenetic regulation, and modulate their enzymatic activities remains elusive. Here we show that the E6...

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Detalles Bibliográficos
Autores principales: Hsu, C-H, Peng, K-L, Jhang, H-C, Lin, C-H, Wu, S-Y, Chiang, C-M, Lee, S-C, Yu, W C Y, Juan, L-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349118/
https://www.ncbi.nlm.nih.gov/pubmed/21963854
http://dx.doi.org/10.1038/onc.2011.415

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