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Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock
Recent reports indicate the possible role of bladder CO(2) as a marker of low perfusion states. To test this hypothesis, shock was induced in six beagle dogs with 1 mg/kg of E. coli lipopolysaccharide, gastric CO(2) (CO(2)-G) was measured with a continuous monitor, and a pulmonary catheter was inser...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Scientific World Journal
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349138/ https://www.ncbi.nlm.nih.gov/pubmed/22593678 http://dx.doi.org/10.1100/2012/360378 |
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author | Seller-Pérez, Gemma Herrera-Gutiérrez, Manuel E. Aragón-González, Cesar Granados, Maria M. Dominguez, Juan M. Navarrete, Rocío Quesada-García, Guillermo Morgaz, Juán Gómez-Villamandos, Rafael |
author_facet | Seller-Pérez, Gemma Herrera-Gutiérrez, Manuel E. Aragón-González, Cesar Granados, Maria M. Dominguez, Juan M. Navarrete, Rocío Quesada-García, Guillermo Morgaz, Juán Gómez-Villamandos, Rafael |
author_sort | Seller-Pérez, Gemma |
collection | PubMed |
description | Recent reports indicate the possible role of bladder CO(2) as a marker of low perfusion states. To test this hypothesis, shock was induced in six beagle dogs with 1 mg/kg of E. coli lipopolysaccharide, gastric CO(2) (CO(2)-G) was measured with a continuous monitor, and a pulmonary catheter was inserted in the bladder to measure CO(2) (CO(2)-B). Levels of CO(2)-B were found to be lower than those of CO(2)-G, with a mean difference of 36.8 mmHg (P < 0.001), and correlation between both measurements was poor (r (2) = 0.16). Even when the correlation between CO(2)-G and ΔCO(2)-G was narrow (r (2) = 0.86), this was not the case for the relationship between CO(2)-B and ΔCO(2)-B (r (2) = 0.29). Finally, the correlation between CO(2)-G and base deficit was good (r (2) = 0.45), which was not the case with the CO(2)-B correlation (r (2) = 0.03). In our experience, bladder CO(2) does not correlate to hemodynamic parameters and does not substitute gastric CO(2) for detection of low perfusion states. |
format | Online Article Text |
id | pubmed-3349138 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Scientific World Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-33491382012-05-16 Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock Seller-Pérez, Gemma Herrera-Gutiérrez, Manuel E. Aragón-González, Cesar Granados, Maria M. Dominguez, Juan M. Navarrete, Rocío Quesada-García, Guillermo Morgaz, Juán Gómez-Villamandos, Rafael ScientificWorldJournal Research Article Recent reports indicate the possible role of bladder CO(2) as a marker of low perfusion states. To test this hypothesis, shock was induced in six beagle dogs with 1 mg/kg of E. coli lipopolysaccharide, gastric CO(2) (CO(2)-G) was measured with a continuous monitor, and a pulmonary catheter was inserted in the bladder to measure CO(2) (CO(2)-B). Levels of CO(2)-B were found to be lower than those of CO(2)-G, with a mean difference of 36.8 mmHg (P < 0.001), and correlation between both measurements was poor (r (2) = 0.16). Even when the correlation between CO(2)-G and ΔCO(2)-G was narrow (r (2) = 0.86), this was not the case for the relationship between CO(2)-B and ΔCO(2)-B (r (2) = 0.29). Finally, the correlation between CO(2)-G and base deficit was good (r (2) = 0.45), which was not the case with the CO(2)-B correlation (r (2) = 0.03). In our experience, bladder CO(2) does not correlate to hemodynamic parameters and does not substitute gastric CO(2) for detection of low perfusion states. The Scientific World Journal 2012-04-19 /pmc/articles/PMC3349138/ /pubmed/22593678 http://dx.doi.org/10.1100/2012/360378 Text en Copyright © 2012 Gemma Seller-Pérez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Seller-Pérez, Gemma Herrera-Gutiérrez, Manuel E. Aragón-González, Cesar Granados, Maria M. Dominguez, Juan M. Navarrete, Rocío Quesada-García, Guillermo Morgaz, Juán Gómez-Villamandos, Rafael Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title | Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title_full | Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title_fullStr | Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title_full_unstemmed | Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title_short | Bladder Mucosal CO(2) Compared with Gastric Mucosal CO(2) as a Marker for Low Perfusion States in Septic Shock |
title_sort | bladder mucosal co(2) compared with gastric mucosal co(2) as a marker for low perfusion states in septic shock |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349138/ https://www.ncbi.nlm.nih.gov/pubmed/22593678 http://dx.doi.org/10.1100/2012/360378 |
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