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Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution

The immune system has the ability to suppress undesirable responses, such as those against commensal bacteria, food, and paternal antigens in placenta pregnancy. The lineage-specific transcription factor Foxp3 orchestrates the development and function of regulatory T cells underlying this immunologi...

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Detalles Bibliográficos
Autores principales:	Andersen, Kristian G., Nissen, Jesper K., Betz, Alexander G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349156/ https://www.ncbi.nlm.nih.gov/pubmed/22590469 http://dx.doi.org/10.3389/fimmu.2012.00113

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