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The differential effects of statins on the metastatic behaviour of prostate cancer
BACKGROUND: Although statins do not affect the incidence of prostate cancer (CaP), usage reduces the risk of clinical progression and mortality. Although statins are known to downregulate the mevalonate pathway, the mechanism by which statins reduce CaP progression is unknown. METHODS: Bone marrow s...
Autores principales: | Brown, M, Hart, C, Tawadros, T, Ramani, V, Sangar, V, Lau, M, Clarke, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349174/ https://www.ncbi.nlm.nih.gov/pubmed/22531631 http://dx.doi.org/10.1038/bjc.2012.138 |
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