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Expression of Forkhead box P3 in tumour cells causes immunoregulatory function of signet ring cell carcinoma of the stomach

BACKGROUND: It was recently reported that the transcription factor Forkhead box P3 (FoxP3) is expressed not only in regulatory T cells (Tregs) but also in cancer cells. The aim of this study was to clarify the clinical significance of FoxP3 expression in gastric carcinoma. METHODS: We performed immu...

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Detalles Bibliográficos
Autores principales: Yoshii, M, Tanaka, H, Ohira, M, Muguruma, K, Iwauchi, T, Lee, T, Sakurai, K, Kubo, N, Yashiro, M, Sawada, T, Hirakawa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349176/
https://www.ncbi.nlm.nih.gov/pubmed/22569001
http://dx.doi.org/10.1038/bjc.2012.141