The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats

In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this...

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Detalles Bibliográficos
Autores principales: Liu, Xianbao, Zhan, Hong, Zeng, Xu, Zhang, Chunfang, Chen, Dunjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349269/
https://www.ncbi.nlm.nih.gov/pubmed/22619485
http://dx.doi.org/10.1155/2012/692467
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author Liu, Xianbao
Zhan, Hong
Zeng, Xu
Zhang, Chunfang
Chen, Dunjin
author_facet Liu, Xianbao
Zhan, Hong
Zeng, Xu
Zhang, Chunfang
Chen, Dunjin
author_sort Liu, Xianbao
collection PubMed
description In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function.
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spelling pubmed-33492692012-05-22 The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats Liu, Xianbao Zhan, Hong Zeng, Xu Zhang, Chunfang Chen, Dunjin Mediators Inflamm Research Article In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function. Hindawi Publishing Corporation 2012 2012-02-15 /pmc/articles/PMC3349269/ /pubmed/22619485 http://dx.doi.org/10.1155/2012/692467 Text en Copyright © 2012 Xianbao Liu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liu, Xianbao
Zhan, Hong
Zeng, Xu
Zhang, Chunfang
Chen, Dunjin
The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title_full The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title_fullStr The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title_full_unstemmed The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title_short The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
title_sort pbde-209 exposure during pregnancy and lactation impairs immune function in rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349269/
https://www.ncbi.nlm.nih.gov/pubmed/22619485
http://dx.doi.org/10.1155/2012/692467
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