The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase

BACKGROUND: GSAO (4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid) and PENAO (4-(N-(S-penicillaminylacetyl)amino) phenylarsonous acid) are tumour metabolism inhibitors that target adenine nucleotide translocase (ANT) of the inner-mitochondrial membrane. Both compounds are currently being trial...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Danielle, Chiu, Joyce, Perrone, Gabriel G, Dilda, Pierre J, Hogg, Philip J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349534/
https://www.ncbi.nlm.nih.gov/pubmed/22448968
http://dx.doi.org/10.1186/1475-2867-12-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349534/
https://www.ncbi.nlm.nih.gov/pubmed/22448968
http://dx.doi.org/10.1186/1475-2867-12-11

Ejemplares similares