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The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase

BACKGROUND: GSAO (4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid) and PENAO (4-(N-(S-penicillaminylacetyl)amino) phenylarsonous acid) are tumour metabolism inhibitors that target adenine nucleotide translocase (ANT) of the inner-mitochondrial membrane. Both compounds are currently being trial...

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Detalles Bibliográficos
Autores principales:	Park, Danielle, Chiu, Joyce, Perrone, Gabriel G, Dilda, Pierre J, Hogg, Philip J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349534/ https://www.ncbi.nlm.nih.gov/pubmed/22448968 http://dx.doi.org/10.1186/1475-2867-12-11

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