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Development of Transgenic Cloned Pig Models of Skin Inflammation by DNA Transposon-Directed Ectopic Expression of Human β1 and α2 Integrin
Integrins constitute a superfamily of transmembrane signaling receptors that play pivotal roles in cutaneous homeostasis by modulating cell growth and differentiation as well as inflammatory responses in the skin. Subrabasal expression of integrins α2 and/or β1 entails hyperproliferation and aberran...
Autores principales: | Staunstrup, Nicklas Heine, Madsen, Johannes, Primo, Maria Nascimento, Li, Juan, Liu, Ying, Kragh, Peter M., Li, Rong, Schmidt, Mette, Purup, Stig, Dagnæs-Hansen, Frederik, Svensson, Lars, Petersen, Thomas K., Callesen, Henrik, Bolund, Lars, Mikkelsen, Jacob Giehm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349713/ https://www.ncbi.nlm.nih.gov/pubmed/22590584 http://dx.doi.org/10.1371/journal.pone.0036658 |
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