Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI experimentally. Hence, it is necessary to develop computational methods for the prediction of potential DTI. Based on complex network theory, three supervised inference methods w...

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Detalles Bibliográficos
Autores principales: Cheng, Feixiong, Liu, Chuang, Jiang, Jing, Lu, Weiqiang, Li, Weihua, Liu, Guixia, Zhou, Weixing, Huang, Jin, Tang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349722/
https://www.ncbi.nlm.nih.gov/pubmed/22589709
http://dx.doi.org/10.1371/journal.pcbi.1002503

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