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Epstein-Barr Virus-Encoded LMP1 Interacts with FGD4 to Activate Cdc42 and Thereby Promote Migration of Nasopharyngeal Carcinoma Cells

Epstein-Barr virus (EBV) is closely associated with nasopharyngeal carcinoma (NPC), a human malignancy notorious for its highly metastatic nature. Among EBV-encoded genes, latent membrane protein 1 (LMP1) is expressed in most NPC tissues and exerts oncogenicity by engaging multiple signaling pathway...

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Detalles Bibliográficos
Autores principales: Liu, Hao-Ping, Chen, Chia-Chun, Wu, Chih-Ching, Huang, Yi-Chuan, Liu, Shu-Chen, Liang, Ying, Chang, Kai-Ping, Chang, Yu-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349753/
https://www.ncbi.nlm.nih.gov/pubmed/22589722
http://dx.doi.org/10.1371/journal.ppat.1002690