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Combination Gene Therapy Targeting On Interleukin-1β and Rankl for Wear Debris Induced Aseptic Loosening

This study investigated the efficacy of a combination gene therapy to repress IL-1 and RANKL for the treatment of particulate debris-induced aseptic loosening, and tried to explore the molecular mechanism the exogenous gene modifications on osteoclastogenesis. RAW cells activated by titanium particl...

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Detalles Bibliográficos
Autores principales:	Wang, Hao, Jia, Tang-Hong, Zacharias, Nora, Du, Hong-Xia, Wooley, Paul H., Yang, Shang-You
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349796/ https://www.ncbi.nlm.nih.gov/pubmed/22318091 http://dx.doi.org/10.1038/gt.2012.1

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