A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells

Previously, we found that high doses of genistein show an inhibitory effect on uterine leiomyoma (UtLM) cell proliferation. In this study, using microarray analysis and Ingenuity Pathways Analysis™, we identified genes (up- or down-regulated, ≥ 1.5 fold, P ≤ 0.001), functions and signaling pathways...

Descripción completa

Detalles Bibliográficos
Autores principales: Di, Xudong, Andrews, Danica M.K., Tucker, Charles J., Yu, Linda, Moore, Alicia B., Zheng, Xiaolin, Castro, Lysandra, Hermon, Tonia, Xiao, Hang, Dixon, Darlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349910/
https://www.ncbi.nlm.nih.gov/pubmed/22228119
http://dx.doi.org/10.3858/emm.2012.44.4.024

Ejemplares similares

Ejemplares similares