Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis

Pathogenesis of dengue involves suppression of immune system leading to development of characteristic presentation of haematological picture of thrombocytopenia and leucopenia. Sometimes, this suppression in immune response is responsible for deterioration in clinical status of the patient in spite...

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Autores principales: Deepak, Desh, Garg, Rakesh, Pawar, Mridula, Banerjee, Neerja, Solanki, Rakesh, Maurya, Indubala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350044/
https://www.ncbi.nlm.nih.gov/pubmed/22606398
http://dx.doi.org/10.1155/2011/896783
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author Deepak, Desh
Garg, Rakesh
Pawar, Mridula
Banerjee, Neerja
Solanki, Rakesh
Maurya, Indubala
author_facet Deepak, Desh
Garg, Rakesh
Pawar, Mridula
Banerjee, Neerja
Solanki, Rakesh
Maurya, Indubala
author_sort Deepak, Desh
collection PubMed
description Pathogenesis of dengue involves suppression of immune system leading to development of characteristic presentation of haematological picture of thrombocytopenia and leucopenia. Sometimes, this suppression in immune response is responsible for deterioration in clinical status of the patient in spite of all specific and supportive therapy. Certain drugs like steroids are used for rescue therapy in conditions like sepsis. We present a novel use of filgrastim as a rescue therapy in a patient with dengue hemorrhagic fever (DHF) with acute respiratory distress syndrome (ARDS), myocarditis, and febrile neutropenia and not responding to standard management.
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spelling pubmed-33500442012-05-17 Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis Deepak, Desh Garg, Rakesh Pawar, Mridula Banerjee, Neerja Solanki, Rakesh Maurya, Indubala Case Rep Anesthesiol Case Report Pathogenesis of dengue involves suppression of immune system leading to development of characteristic presentation of haematological picture of thrombocytopenia and leucopenia. Sometimes, this suppression in immune response is responsible for deterioration in clinical status of the patient in spite of all specific and supportive therapy. Certain drugs like steroids are used for rescue therapy in conditions like sepsis. We present a novel use of filgrastim as a rescue therapy in a patient with dengue hemorrhagic fever (DHF) with acute respiratory distress syndrome (ARDS), myocarditis, and febrile neutropenia and not responding to standard management. Hindawi Publishing Corporation 2011 2011-11-10 /pmc/articles/PMC3350044/ /pubmed/22606398 http://dx.doi.org/10.1155/2011/896783 Text en Copyright © 2011 Desh Deepak et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Deepak, Desh
Garg, Rakesh
Pawar, Mridula
Banerjee, Neerja
Solanki, Rakesh
Maurya, Indubala
Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title_full Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title_fullStr Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title_full_unstemmed Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title_short Filgrastim as a Rescue Therapy for Persistent Neutropenia in a Case of Dengue Hemorrhagic Fever with Acute Respiratory Distress Syndrome and Myocarditis
title_sort filgrastim as a rescue therapy for persistent neutropenia in a case of dengue hemorrhagic fever with acute respiratory distress syndrome and myocarditis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350044/
https://www.ncbi.nlm.nih.gov/pubmed/22606398
http://dx.doi.org/10.1155/2011/896783
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