Orbitotemporal Neurofibromatosis: Case Report

Plexiform neurofibromas occur in about 60% of neurofibromatosis type 1(NF-1) patients and can lead to severe morbidity by disfigurement or compression of vital structures. Moreover, these tumors can undergo malignant transformation. Both focal and localized bone abnormalities are part of the phenoty...

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Autores principales: Balasubramanyam, Mahalakshmi, Cugati, Goutham, Mukherjee, Bipasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350063/
https://www.ncbi.nlm.nih.gov/pubmed/22606495
http://dx.doi.org/10.1155/2012/498186
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author Balasubramanyam, Mahalakshmi
Cugati, Goutham
Mukherjee, Bipasha
author_facet Balasubramanyam, Mahalakshmi
Cugati, Goutham
Mukherjee, Bipasha
author_sort Balasubramanyam, Mahalakshmi
collection PubMed
description Plexiform neurofibromas occur in about 60% of neurofibromatosis type 1(NF-1) patients and can lead to severe morbidity by disfigurement or compression of vital structures. Moreover, these tumors can undergo malignant transformation. Both focal and localized bone abnormalities are part of the phenotypic expression of NF-1. We report a rare case of severe cranioorbital plexiform neurofibromatosis in a young male and discuss the classification, clinical features, and various treatment options of orbit-temporal neurofibromatosis type 1.
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spelling pubmed-33500632012-05-17 Orbitotemporal Neurofibromatosis: Case Report Balasubramanyam, Mahalakshmi Cugati, Goutham Mukherjee, Bipasha Case Rep Ophthalmol Med Case Report Plexiform neurofibromas occur in about 60% of neurofibromatosis type 1(NF-1) patients and can lead to severe morbidity by disfigurement or compression of vital structures. Moreover, these tumors can undergo malignant transformation. Both focal and localized bone abnormalities are part of the phenotypic expression of NF-1. We report a rare case of severe cranioorbital plexiform neurofibromatosis in a young male and discuss the classification, clinical features, and various treatment options of orbit-temporal neurofibromatosis type 1. Hindawi Publishing Corporation 2012 2012-03-29 /pmc/articles/PMC3350063/ /pubmed/22606495 http://dx.doi.org/10.1155/2012/498186 Text en Copyright © 2012 Mahalakshmi Balasubramanyam et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Balasubramanyam, Mahalakshmi
Cugati, Goutham
Mukherjee, Bipasha
Orbitotemporal Neurofibromatosis: Case Report
title Orbitotemporal Neurofibromatosis: Case Report
title_full Orbitotemporal Neurofibromatosis: Case Report
title_fullStr Orbitotemporal Neurofibromatosis: Case Report
title_full_unstemmed Orbitotemporal Neurofibromatosis: Case Report
title_short Orbitotemporal Neurofibromatosis: Case Report
title_sort orbitotemporal neurofibromatosis: case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350063/
https://www.ncbi.nlm.nih.gov/pubmed/22606495
http://dx.doi.org/10.1155/2012/498186
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AT cugatigoutham orbitotemporalneurofibromatosiscasereport
AT mukherjeebipasha orbitotemporalneurofibromatosiscasereport

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