Accidental Intrathecal Injection of Tranexamic Acid

Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from simila...

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Detalles Bibliográficos
Autores principales: Mahmoud, Khaled, Ammar, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350102/
https://www.ncbi.nlm.nih.gov/pubmed/22606407
http://dx.doi.org/10.1155/2012/646028
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author Mahmoud, Khaled
Ammar, Amany
author_facet Mahmoud, Khaled
Ammar, Amany
author_sort Mahmoud, Khaled
collection PubMed
description Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced severe pain in the back and gluteal region upon injection in association with systemic hypertension and tachycardia followed by generalized myoclonic seizures and ventricular fibrillation.
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spelling pubmed-33501022012-05-17 Accidental Intrathecal Injection of Tranexamic Acid Mahmoud, Khaled Ammar, Amany Case Rep Anesthesiol Case Report Tranexamic acid (TXA) is a popular antifibrinolytic drug that is commonly used in patients with bleeding disorder. Major morbidities and mortalities have been reported following inadvertent intrathecal injection of TXA. In this paper, inadvertent intrathecal injection of TXA has resulted from similarities in appearance between TXA and heavy bupivacaine 0.5% ampoules. The patient experienced severe pain in the back and gluteal region upon injection in association with systemic hypertension and tachycardia followed by generalized myoclonic seizures and ventricular fibrillation. Hindawi Publishing Corporation 2012 2012-03-26 /pmc/articles/PMC3350102/ /pubmed/22606407 http://dx.doi.org/10.1155/2012/646028 Text en Copyright © 2012 K. Mahmoud and A. Ammar. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mahmoud, Khaled
Ammar, Amany
Accidental Intrathecal Injection of Tranexamic Acid
title Accidental Intrathecal Injection of Tranexamic Acid
title_full Accidental Intrathecal Injection of Tranexamic Acid
title_fullStr Accidental Intrathecal Injection of Tranexamic Acid
title_full_unstemmed Accidental Intrathecal Injection of Tranexamic Acid
title_short Accidental Intrathecal Injection of Tranexamic Acid
title_sort accidental intrathecal injection of tranexamic acid
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350102/
https://www.ncbi.nlm.nih.gov/pubmed/22606407
http://dx.doi.org/10.1155/2012/646028
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