Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation

A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring l...

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Detalles Bibliográficos
Autores principales: Tran, Nguyen P., Katcher, Jeremy, Rohman, Erin, Hall, Mary Francis, Michael, Christie F., Miyairi, Isao, Lew, D. Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350173/
https://www.ncbi.nlm.nih.gov/pubmed/22606516
http://dx.doi.org/10.1155/2011/562620
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author Tran, Nguyen P.
Katcher, Jeremy
Rohman, Erin
Hall, Mary Francis
Michael, Christie F.
Miyairi, Isao
Lew, D. Betty
author_facet Tran, Nguyen P.
Katcher, Jeremy
Rohman, Erin
Hall, Mary Francis
Michael, Christie F.
Miyairi, Isao
Lew, D. Betty
author_sort Tran, Nguyen P.
collection PubMed
description A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection.
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spelling pubmed-33501732012-05-17 Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation Tran, Nguyen P. Katcher, Jeremy Rohman, Erin Hall, Mary Francis Michael, Christie F. Miyairi, Isao Lew, D. Betty Case Rep Pediatr Case Report A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic selection. Hindawi Publishing Corporation 2011 2011-11-24 /pmc/articles/PMC3350173/ /pubmed/22606516 http://dx.doi.org/10.1155/2011/562620 Text en Copyright © 2011 Nguyen P. Tran et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tran, Nguyen P.
Katcher, Jeremy
Rohman, Erin
Hall, Mary Francis
Michael, Christie F.
Miyairi, Isao
Lew, D. Betty
Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title_full Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title_fullStr Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title_full_unstemmed Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title_short Vancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
title_sort vancomycin hypersensitivity diagnosed by lymphocyte blast transformation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350173/
https://www.ncbi.nlm.nih.gov/pubmed/22606516
http://dx.doi.org/10.1155/2011/562620
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