Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist

A 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography rev...

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Detalles Bibliográficos
Autores principales: Iblher, Niklas, Stark, Gerd Bjoern, Penna, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350209/
https://www.ncbi.nlm.nih.gov/pubmed/22606575
http://dx.doi.org/10.1155/2011/347523
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author Iblher, Niklas
Stark, Gerd Bjoern
Penna, Vincenzo
author_facet Iblher, Niklas
Stark, Gerd Bjoern
Penna, Vincenzo
author_sort Iblher, Niklas
collection PubMed
description A 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography revealed blockage of perfusion of the 4th and 5th digits. Despite intra-arterial lysis, heparinisation, and vasodilatation, perfusion could not be reinstalled. Necrosis of the distal phalanges of the 4th and 5th digits developed, which had to be treated with amputation. The pathomechanism of tissue damage and the treatment options after intra-arterial injections are reviewed and discussed.
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spelling pubmed-33502092012-05-17 Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist Iblher, Niklas Stark, Gerd Bjoern Penna, Vincenzo Case Rep Surg Case Report A 75-year-old woman presented with progressing pain, cyanosis, and hypaesthesia in her left hand after an intra-articular injection with diazepam into the wrist for osteoarthritis-related pain. Due to an iatrogenic intra-arterial injection, malperfusion of the ulnar digits developed. Angiography revealed blockage of perfusion of the 4th and 5th digits. Despite intra-arterial lysis, heparinisation, and vasodilatation, perfusion could not be reinstalled. Necrosis of the distal phalanges of the 4th and 5th digits developed, which had to be treated with amputation. The pathomechanism of tissue damage and the treatment options after intra-arterial injections are reviewed and discussed. Hindawi Publishing Corporation 2011 2011-09-14 /pmc/articles/PMC3350209/ /pubmed/22606575 http://dx.doi.org/10.1155/2011/347523 Text en Copyright © 2011 Niklas Iblher et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Iblher, Niklas
Stark, Gerd Bjoern
Penna, Vincenzo
Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title_full Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title_fullStr Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title_full_unstemmed Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title_short Necrosis of the 4th and 5th Digits after Intra-Articular Injection of Diazepam into the Wrist
title_sort necrosis of the 4th and 5th digits after intra-articular injection of diazepam into the wrist
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350209/
https://www.ncbi.nlm.nih.gov/pubmed/22606575
http://dx.doi.org/10.1155/2011/347523
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AT pennavincenzo necrosisofthe4thand5thdigitsafterintraarticularinjectionofdiazepamintothewrist

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