Categorization of 77 dystrophin exons into 5 groups by a decision tree using indexes of splicing regulatory factors as decision markers

BACKGROUND: Duchenne muscular dystrophy, a fatal muscle-wasting disease, is characterized by dystrophin deficiency caused by mutations in the dystrophin gene. Skipping of a target dystrophin exon during splicing with antisense oligonucleotides is attracting much attention as the most plausible way t...

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Detalles Bibliográficos
Autores principales: Malueka, Rusdy Ghazali, Takaoka, Yutaka, Yagi, Mariko, Awano, Hiroyuki, Lee, Tomoko, Dwianingsih, Ery Kus, Nishida, Atsushi, Takeshima, Yasuhiro, Matsuo, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350383/
https://www.ncbi.nlm.nih.gov/pubmed/22462762
http://dx.doi.org/10.1186/1471-2156-13-23

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