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High-dose fasudil preserves postconditioning against myocardial infarction under hyperglycemia in rats: role of mitochondrial KATP channels

BACKGROUND: The current study was carried out to determine whether fasudil hydrochloride (fasudil), a Rho-kinase inhibitor, has myocardial postconditioning (PostC) activity under hyperglycemia as well as normoglycemia, and if so, whether the effects could be mediated by mitochondrial ATP-sensitive p...

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Detalles Bibliográficos
Autores principales:	Ichinomiya, Taiga, Cho, Sungsam, Higashijima, Ushio, Matsumoto, Shuhei, Maekawa, Takuji, Sumikawa, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350454/ https://www.ncbi.nlm.nih.gov/pubmed/22436066 http://dx.doi.org/10.1186/1475-2840-11-28

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