Syndecan-2 promotes perineural invasion and cooperates with K-ras to induce an invasive pancreatic cancer cell phenotype

BACKGROUND: We have identified syndecan-2 as a protein potentially involved in perineural invasion of pancreatic adenocarcinoma (PDAC) cells. METHODS: Syndecan-2 (SDC-2) expression was analyzed in human normal pancreas, chronic pancreatitis and PDAC tissues. Functional in vitro assays were carried o...

Descripción completa

Detalles Bibliográficos
Autores principales: De Oliveira, Tiago, Abiatari, Ivane, Raulefs, Susanne, Sauliunaite, Danguole, Erkan, Mert, Kong, Bo, Friess, Helmut, Michalski, Christoph W, Kleeff, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350462/
https://www.ncbi.nlm.nih.gov/pubmed/22471946
http://dx.doi.org/10.1186/1476-4598-11-19

Ejemplares similares

Ejemplares similares