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Bmi1 Confers Resistance to Oxidative Stress on Hematopoietic Stem Cells

BACKGROUND: The polycomb-group (PcG) proteins function as general regulators of stem cells. We previously reported that retrovirus-mediated overexpression of Bmi1, a gene encoding a core component of polycomb repressive complex (PRC) 1, maintained self-renewing hematopoietic stem cells (HSCs) during...

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Detalles Bibliográficos
Autores principales:	Nakamura, Shunsuke, Oshima, Motohiko, Yuan, Jin, Saraya, Atsunori, Miyagi, Satoru, Konuma, Takaaki, Yamazaki, Satoshi, Osawa, Mitsujiro, Nakauchi, Hiromitsu, Koseki, Haruhiko, Iwama, Atsushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350495/ https://www.ncbi.nlm.nih.gov/pubmed/22606246 http://dx.doi.org/10.1371/journal.pone.0036209

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