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Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis
Centrioles organize the centrosome, and accurate control of their number is critical for the maintenance of genomic integrity. Centrioles duplicate once per cell cycle, and duplication is coordinated by Polo-like kinase 4 (Plk4). We previously demonstrated that Plk4 accumulation is autoregulated by...
Autores principales: | Holland, Andrew J., Fachinetti, Daniele, Da Cruz, Sandrine, Zhu, Quan, Vitre, Benjamin, Lince-Faria, Mariana, Chen, Denaly, Parish, Nicole, Verma, Inder M., Bettencourt-Dias, Monica, Cleveland, Don W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350549/ https://www.ncbi.nlm.nih.gov/pubmed/22456511 http://dx.doi.org/10.1091/mbc.E11-12-1043 |
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