Geometry sensing by dendritic cells dictates spatial organization and PGE(2)-induced dissolution of podosomes

Assembly and disassembly of adhesion structures such as focal adhesions (FAs) and podosomes regulate cell adhesion and differentiation. On antigen-presenting dendritic cells (DCs), acquisition of a migratory and immunostimulatory phenotype depends on podosome dissolution by prostaglandin E(2) (PGE(2...

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Detalles Bibliográficos
Autores principales: van den Dries, Koen, van Helden, Suzanne F. G., Riet, Joost te, Diez-Ahedo, Ruth, Manzo, Carlo, Oud, Machteld M., van Leeuwen, Frank N., Brock, Roland, Garcia-Parajo, Maria F., Cambi, Alessandra, Figdor, Carl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350765/
https://www.ncbi.nlm.nih.gov/pubmed/22204022
http://dx.doi.org/10.1007/s00018-011-0908-y

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