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Proteomic Characterization of a Mouse Model of Familial Danish Dementia

A dominant mutation in the ITM2B/BRI2 gene causes familial Danish dementia (FDD) in humans. To model FDD in animal systems, a knock-in approach was recently implemented in mice expressing a wild-type and mutant allele, which bears the FDD-associated mutation. Since these FDD(KI) mice show behavioura...

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Detalles Bibliográficos
Autores principales:	Vitale, Monica, Renzone, Giovanni, Matsuda, Shuji, Scaloni, Andrea, D'Adamio, Luciano, Zambrano, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350990/ https://www.ncbi.nlm.nih.gov/pubmed/22619496 http://dx.doi.org/10.1155/2012/728178

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