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Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates
BACKGROUND: Bisphosphonates possess strong affinity to bone. (99m)Tc bisphosphonate complexes are widely used for bone scintigraphy. For positron emission tomography (PET) bone imaging, Ga-68-based PET tracers based on bisphosphonates are highly desirable. FINDINGS: Two trimeric bisphosphonate conju...
Autores principales: | Notni, Johannes, Plutnar, Jan, Wester, Hans-Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351026/ https://www.ncbi.nlm.nih.gov/pubmed/22464278 http://dx.doi.org/10.1186/2191-219X-2-13 |
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