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Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer
BACKGROUND: Cancers often arise within an area of cells (e.g. an epithelial patch) that is predisposed to the development of cancer, i.e. a "field of cancerization" or "field defect." Sporadic colon cancer is characterized by an elevated mutation rate and genomic instability. If...
Autores principales: | Facista, Alexander, Nguyen, Huy, Lewis, Cristy, Prasad, Anil R, Ramsey, Lois, Zaitlin, Beryl, Nfonsam, Valentine, Krouse, Robert S, Bernstein, Harris, Payne, Claire M, Stern, Stephen, Oatman, Nicole, Banerjee, Bhaskar, Bernstein, Carol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351028/ https://www.ncbi.nlm.nih.gov/pubmed/22494821 http://dx.doi.org/10.1186/2041-9414-3-3 |
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