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Kinetics and mechanism of G-quadruplex formation and conformational switch in a G-quadruplex of PS2.M induced by Pb(2+)

DNA sequences with guanine repeats can form G-quartets that adopt G-quadruplex structures in the presence of specific metal ions. Using circular dichroism (CD) and ultraviolet-visible (UV–Vis) spectroscopy, we determined the spectral characteristics and the overall conformation of a G-quadruplex of...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhu, Hong, Zheng, Bin, Cheng, Sheng, Fu, Yan, Li, Wei, Lau, Tai-Chu, Liang, Haojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351173/
https://www.ncbi.nlm.nih.gov/pubmed/22241774
http://dx.doi.org/10.1093/nar/gkr1310

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