Cargando…

Genome-wide occupancy links Hoxa2 to Wnt–β-catenin signaling in mouse embryonic development

The regulation of gene expression is central to developmental programs and largely depends on the binding of sequence-specific transcription factors with cis-regulatory elements in the genome. Hox transcription factors specify the spatial coordinates of the body axis in all animals with bilateral sy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Donaldson, Ian J., Amin, Shilu, Hensman, James J., Kutejova, Eva, Rattray, Magnus, Lawrence, Neil, Hayes, Andrew, Ward, Christopher M., Bobola, Nicoletta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351182/ https://www.ncbi.nlm.nih.gov/pubmed/22223247 http://dx.doi.org/10.1093/nar/gkr1240

Ejemplares similares

Hoxa2 Selectively Enhances Meis Binding to Change a Branchial Arch Ground State
por: Amin, Shilu, et al.
Publicado: (2015)

Differential Distribution of the Ca (2+) Regulator Pcp4 in the Branchial Arches Is Regulated by Hoxa2
por: Anderson, Megan, et al.
Publicado: (2013)

Molecular Characterization of HOXA2 and HOXA3 Binding Properties
por: Mallen, Joshua, et al.
Publicado: (2021)

Uncovering tissue-specific binding features from differential deep learning
por: Phuycharoen, Mike, et al.
Publicado: (2020)

Hierarchical Bayesian modelling of gene expression time series across irregularly sampled replicates and clusters
por: Hensman, James, et al.
Publicado: (2013)

BGP: identifying gene-specific branching dynamics from single-cell data with a branching Gaussian process
por: Boukouvalas, Alexis, et al.
Publicado: (2018)

MicroRNA-873 targets HOXA9 to inhibit the aggressive phenotype of osteosarcoma by deactivating the Wnt/β-catenin pathway
por: Liu, Yilin, et al.
Publicado: (2022)

E-cadherin involved in inactivation of WNT/β-catenin signalling in urothelial carcinoma and normal urothelial cells
por: Thievessen, I, et al.
Publicado: (2003)

miR-429 inhibits osteosarcoma progression by targeting HOXA9 through suppressing Wnt/β-catenin signaling pathway
por: Sun, Liangzhi, et al.
Publicado: (2020)

E-Cadherin Acts as a Regulator of Transcripts Associated with a Wide Range of Cellular Processes in Mouse Embryonic Stem Cells
por: Soncin, Francesca, et al.
Publicado: (2011)

Wnt/beta-catenin signaling in embryonic stem cell converted tumor cells
por: Peng, Xinrong, et al.
Publicado: (2012)

MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9
por: Zhang, Zi-Feng, et al.
Publicado: (2017)

HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53
por: Ma, Hong-Mei, et al.
Publicado: (2020)

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion
por: Little, Gillian H., et al.
Publicado: (2012)

GATA-1 genome-wide occupancy associates with distinct epigenetic profiles in mouse fetal liver erythropoiesis
por: Papadopoulos, Giorgio L., et al.
Publicado: (2013)

A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells
por: Chin, Alana M., et al.
Publicado: (2016)

Fast and accurate approximate inference of transcript expression from RNA-seq data
por: Hensman, James, et al.
Publicado: (2015)

The Wnt/β-catenin signaling pathway is involved in regulating feather growth of embryonic chicks
por: Xie, W.Y., et al.
Publicado: (2020)

Wnt/β-catenin signaling promotes neurogenesis in the diencephalospinal dopaminergic system of embryonic zebrafish
por: Westphal, Markus, et al.
Publicado: (2022)

Retraction: MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9
por: Zhang, Zi-Feng, et al.
Publicado: (2022)

HOT or not: examining the basis of high-occupancy target regions
por: Wreczycka, Katarzyna, et al.
Publicado: (2019)

Endogenous Wnt/β-Catenin Signaling Is Required for Cardiac Differentiation in Human Embryonic Stem Cells
por: Paige, Sharon L., et al.
Publicado: (2010)

Long Noncoding RNA ZFPM2-AS1 Knockdown Restrains the Development of Retinoblastoma by Modulating the MicroRNA-515/HOXA1/Wnt/β-Catenin Axis
por: Lyv, Xueman, et al.
Publicado: (2020)

HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas
por: Jäger, Daniela, et al.
Publicado: (2017)

Aberrant WNT/β-catenin signaling in parathyroid carcinoma
por: Svedlund, Jessica, et al.
Publicado: (2010)

DNA physical properties determine nucleosome occupancy from yeast to fly
por: Miele, Vincent, et al.
Publicado: (2008)

Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq
por: Bottomly, Daniel, et al.
Publicado: (2010)

Wnt6 influences the viability of mouse embryonic palatal mesenchymal cells via the β-catenin pathway
por: Jiang, Zheng, et al.
Publicado: (2017)

Wnt/β-catenin signaling pathway safeguards epigenetic stability and homeostasis of mouse embryonic stem cells
por: Theka, Ilda, et al.
Publicado: (2019)

Wnt/β-catenin Pathway-Mediated PPARδ Expression during Embryonic Development Differentiation and Disease
por: Sidrat, Tabinda, et al.
Publicado: (2021)

From DNA binding to transcriptional activation: Is the TALE complete?
por: Bobola, Nicoletta
Publicado: (2017)

Tup1 stabilizes promoter nucleosome positioning and occupancy at transcriptionally plastic genes
por: Rizzo, Jason M., et al.
Publicado: (2011)

Genetic and phenotypic continuum of HOXA genes: A case with double HOXA9/HOXA13 mutations
por: Jaouadi, Hager, et al.
Publicado: (2023)

Exploration of the effects of a degS mutant on the growth of Vibrio cholerae and the global regulatory function of degS by RNA sequencing
por: Huang, Jian, et al.
Publicado: (2019)

HIF2α induces cardiomyogenesis via Wnt/β-catenin signaling in mouse embryonic stem cells
por: Sun, Xiaotian, et al.
Publicado: (2015)

Non-parametric modelling of temporal and spatial counts data from RNA-seq experiments
por: BinTayyash, Nuha, et al.
Publicado: (2021)

Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells
por: Rhee, Catherine, et al.
Publicado: (2017)

Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells
por: Bakoulis, Stylianos, et al.
Publicado: (2022)

Hypermethylation of genes in testicular embryonal carcinomas
por: Cheung, Hoi-Hung, et al.
Publicado: (2016)

microRNA‐100 functions as a tumor suppressor in non‐small cell lung cancer via regulating epithelial‐mesenchymal transition and Wnt/β‐catenin by targeting HOXA1
por: Han, Weizhong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_4ijgvj8nnc992qhgnfloc6a1up