Involvement of residues of the ϕ29 terminal protein intermediate and priming domains in the formation of a stable and functional heterodimer with the replicative DNA polymerase

Bacteriophage ϕ29 genome consists of a linear double-stranded DNA with a terminal protein (TP) covalently linked to each 5′ end (TP-DNA) that together with a specific sequence constitutes the replication origins. To initiate replication, the DNA polymerase forms a heterodimer with a free TP that rec...

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Detalles Bibliográficos
Autores principales: del Prado, Alicia, Villar, Laurentino, de Vega, Miguel, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351185/
https://www.ncbi.nlm.nih.gov/pubmed/22210885
http://dx.doi.org/10.1093/nar/gkr1283

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