Lack of Cul4b, an E3 Ubiquitin Ligase Component, Leads to Embryonic Lethality and Abnormal Placental Development

Cullin-RING ligases (CRLs) complexes participate in the regulation of diverse cellular processes, including cell cycle progression, transcription, signal transduction and development. Serving as the scaffold protein, cullins are crucial for the assembly of ligase complexes, which recognize and targe...

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Detalles Bibliográficos
Autores principales: Jiang, Baichun, Zhao, Wei, Yuan, Jupeng, Qian, Yanyan, Sun, Wenjie, Zou, Yongxin, Guo, Chenhong, Chen, Bingxi, Shao, Changshun, Gong, Yaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351389/
https://www.ncbi.nlm.nih.gov/pubmed/22606329
http://dx.doi.org/10.1371/journal.pone.0037070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351389/
https://www.ncbi.nlm.nih.gov/pubmed/22606329
http://dx.doi.org/10.1371/journal.pone.0037070

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