Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs

PURPOSE: To define gene expression changes associated with diabetic retinopathy in a mouse model using next generation sequencing, and to utilize transcriptome signatures to assess molecular pathways by which pharmacological agents inhibit diabetic retinopathy. METHODS: We applied a high throughput...

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Detalles Bibliográficos
Autores principales: Kandpal, Raj P., Rajasimha, Harsha K., Brooks, Matthew J., Nellissery, Jacob, Wan, Jun, Qian, Jiang, Kern, Timothy S., Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351417/
https://www.ncbi.nlm.nih.gov/pubmed/22605924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351417/
https://www.ncbi.nlm.nih.gov/pubmed/22605924

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