Cargando…
Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs
PURPOSE: To define gene expression changes associated with diabetic retinopathy in a mouse model using next generation sequencing, and to utilize transcriptome signatures to assess molecular pathways by which pharmacological agents inhibit diabetic retinopathy. METHODS: We applied a high throughput...
Autores principales: | Kandpal, Raj P., Rajasimha, Harsha K., Brooks, Matthew J., Nellissery, Jacob, Wan, Jun, Qian, Jiang, Kern, Timothy S., Swaroop, Anand |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351417/ https://www.ncbi.nlm.nih.gov/pubmed/22605924 |
Ejemplares similares
-
Next-generation sequencing facilitates quantitative analysis of wild-type and Nrl(−/−) retinal transcriptomes
por: Brooks, Matthew J., et al.
Publicado: (2011) -
Genetic components in diabetic retinopathy
por: Mishra, Bibhudatta, et al.
Publicado: (2016) -
Mitochondrial Respiration in Outer Retina Contributes to Light-Evoked Increase in Hydration In Vivo
por: Berkowitz, Bruce A., et al.
Publicado: (2018) -
Genetic architecture of retinal and macular degenerative diseases: the promise and challenges of next-generation sequencing
por: Ratnapriya, Rinki, et al.
Publicado: (2013) -
Next-generation RNA sequencing elucidates transcriptomic signatures of pathophysiologic nerve regeneration
por: Warner, Wesley S., et al.
Publicado: (2023)