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Evolutionary Dynamics of Co-Segregating Gene Clusters Associated with Complex Diseases

BACKGROUND: The distribution of human disease-associated mutations is not random across the human genome. Despite the fact that natural selection continually removes disease-associated mutations, an enrichment of these variants can be observed in regions of low recombination. There are a number of m...

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Detalles Bibliográficos
Autores principales:	Preuss, Christoph, Riemenschneider, Mona, Wiedmann, David, Stoll, Monika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351447/ https://www.ncbi.nlm.nih.gov/pubmed/22606245 http://dx.doi.org/10.1371/journal.pone.0036205

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