Rapid Transcriptional Pulsing Dynamics of High Expressing Retroviral Transgenes in Embryonic Stem Cells

Single cell imaging studies suggest that transcription is not continuous and occurs as discrete pulses of gene activity. To study mechanisms by which retroviral transgenes can transcribe to high levels, we used the MS2 system to visualize transcriptional dynamics of high expressing proviral integrat...

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Detalles Bibliográficos
Autores principales: Lo, Mandy Y. M., Rival-Gervier, Sylvie, Pasceri, Peter, Ellis, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351450/
https://www.ncbi.nlm.nih.gov/pubmed/22606340
http://dx.doi.org/10.1371/journal.pone.0037130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351450/
https://www.ncbi.nlm.nih.gov/pubmed/22606340
http://dx.doi.org/10.1371/journal.pone.0037130

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