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Neuregulin Promotes Incomplete Autophagy of Prostate Cancer Cells That Is Independent of mTOR Pathway Inhibition

BACKGROUND: Growth factors activating the ErbB receptors have been described in prostate tumors. The androgen dependent prostate cancer cell line, LNCaP, expresses the ErbB-1, ErbB-2 and ErbB-3 receptor tyrosine kinases. Previously, it was demonstrated that NRG activates ErbB-2/ErbB-3 heterodimers t...

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Detalles Bibliográficos
Autores principales:	Schmukler, Eran, Shai, Ben, Ehrlich, Marcelo, Pinkas-Kramarski, Ronit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351469/ https://www.ncbi.nlm.nih.gov/pubmed/22606295 http://dx.doi.org/10.1371/journal.pone.0036828

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