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A convenient route to optically pure α-alkyl-β-(sec-amino)alanines

The cyclization of N-Boc-α-alkylserines to corresponding β-lactones under Mitsunobu reaction conditions and the ring opening with heterocyclic amines (pyrrolidine, piperidine, morpholine and thiomorpholine) produced N-Boc-α-alkyl-β-(sec-amino)alanines. The removal of the Boc group gives di-hydrochlo...

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Detalles Bibliográficos
Autores principales:	Olma, A., Lasota, A., Kudaj, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2011
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351611/ https://www.ncbi.nlm.nih.gov/pubmed/21847610 http://dx.doi.org/10.1007/s00726-011-1055-3

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