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Intake levels of dietary long-chain PUFAs modify the association between genetic variation in FADS and LDL-C

Polymorphisms of the FA desaturase (FADS) gene cluster have been associated with LDL, HDL, and triglyceride concentrations. Because FADS converts α-linolenic acid (ALA) and linoleic acid into PUFAs, we investigated the interaction between different PUFA intakes and the FADS polymorphism rs174547 (T&...

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Detalles Bibliográficos
Autores principales: Hellstrand, S., Sonestedt, E., Ericson, U., Gullberg, B., Wirfält, E., Hedblad, B., Orho-Melander, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351825/
https://www.ncbi.nlm.nih.gov/pubmed/22451038
http://dx.doi.org/10.1194/jlr.P023721