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TME quality in rectal cancer surgery

BACKGROUND: The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed rectal tumours have an optimal TME quality. Patients: During a period of 36 mon...

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Autores principales: Herzog, T, Belyaev, O, Chromik, AM, Weyhe, D, Mueller, CA, Munding, J, Tannapfel, A, Uhl, W, Seelig, MH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351953/
https://www.ncbi.nlm.nih.gov/pubmed/20696640
http://dx.doi.org/10.1186/2047-783X-15-7-292
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author Herzog, T
Belyaev, O
Chromik, AM
Weyhe, D
Mueller, CA
Munding, J
Tannapfel, A
Uhl, W
Seelig, MH
author_facet Herzog, T
Belyaev, O
Chromik, AM
Weyhe, D
Mueller, CA
Munding, J
Tannapfel, A
Uhl, W
Seelig, MH
author_sort Herzog, T
collection PubMed
description BACKGROUND: The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed rectal tumours have an optimal TME quality. Patients: During a period of 36 months we performed 103 rectal resections. The majority of patients (76%; 78/103) received an anterior resection. The remaining patients underwent either abdominoperineal resection (16%; 17/103), Hartmann's procedure (6%; 6/103) or colectomy (2%; 2/103). RESULTS: In 90% (93/103) TME quality control could be performed. 99% (92/93) of resected tumours had optimal TME quality. In 1% (1/93) the mesorectum was nearly complete. None of the removed tumours had an incomplete mesorectum. In 98% (91/93) the circumferential resection margin was negative. Major surgical complications occurred in 17% (18/103). 5% (4/78) of patients with anterior resection had anastomotic leakage. 17% (17/103) developed wound infections. Mortality after elective surgery was 4% (4/95). CONCLUSION: Optimal TME quality results can be achieved in all stages of rectal cancer with a rate of morbidity and mortality comparable to the results from the literature. Future studies should evaluate outcome and local recurrence in accordance to the degree of TME quality.
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spelling pubmed-33519532012-05-16 TME quality in rectal cancer surgery Herzog, T Belyaev, O Chromik, AM Weyhe, D Mueller, CA Munding, J Tannapfel, A Uhl, W Seelig, MH Eur J Med Res Research BACKGROUND: The concept of total mesorectal excision has revolutionised rectal cancer surgery. TME reduces the rate of local recurrence and tumour associated mortality. However, in clinical trials only 50% of the removed rectal tumours have an optimal TME quality. Patients: During a period of 36 months we performed 103 rectal resections. The majority of patients (76%; 78/103) received an anterior resection. The remaining patients underwent either abdominoperineal resection (16%; 17/103), Hartmann's procedure (6%; 6/103) or colectomy (2%; 2/103). RESULTS: In 90% (93/103) TME quality control could be performed. 99% (92/93) of resected tumours had optimal TME quality. In 1% (1/93) the mesorectum was nearly complete. None of the removed tumours had an incomplete mesorectum. In 98% (91/93) the circumferential resection margin was negative. Major surgical complications occurred in 17% (18/103). 5% (4/78) of patients with anterior resection had anastomotic leakage. 17% (17/103) developed wound infections. Mortality after elective surgery was 4% (4/95). CONCLUSION: Optimal TME quality results can be achieved in all stages of rectal cancer with a rate of morbidity and mortality comparable to the results from the literature. Future studies should evaluate outcome and local recurrence in accordance to the degree of TME quality. BioMed Central 2010-07-26 /pmc/articles/PMC3351953/ /pubmed/20696640 http://dx.doi.org/10.1186/2047-783X-15-7-292 Text en Copyright ©2010 I. Holzapfel Publishers
spellingShingle Research
Herzog, T
Belyaev, O
Chromik, AM
Weyhe, D
Mueller, CA
Munding, J
Tannapfel, A
Uhl, W
Seelig, MH
TME quality in rectal cancer surgery
title TME quality in rectal cancer surgery
title_full TME quality in rectal cancer surgery
title_fullStr TME quality in rectal cancer surgery
title_full_unstemmed TME quality in rectal cancer surgery
title_short TME quality in rectal cancer surgery
title_sort tme quality in rectal cancer surgery
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351953/
https://www.ncbi.nlm.nih.gov/pubmed/20696640
http://dx.doi.org/10.1186/2047-783X-15-7-292
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