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Gasperini syndrome as clinical manifestation of pontine demyelination

The Gasperini syndrome is a very rare brainstem disease characterized by the typical combination of ipsilateral lesions of the cranial nerves V-VII and dissociated contralateral hemihypesthesia, whereas both contralateral and ipsilateral hypacusis was described. Since the first description in 1912,...

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Autores principales: Krasnianski, M, Müller, T, Zierz, S, Winterholler, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351973/
https://www.ncbi.nlm.nih.gov/pubmed/19748860
http://dx.doi.org/10.1186/2047-783X-14-9-413
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author Krasnianski, M
Müller, T
Zierz, S
Winterholler, M
author_facet Krasnianski, M
Müller, T
Zierz, S
Winterholler, M
author_sort Krasnianski, M
collection PubMed
description The Gasperini syndrome is a very rare brainstem disease characterized by the typical combination of ipsilateral lesions of the cranial nerves V-VII and dissociated contralateral hemihypesthesia, whereas both contralateral and ipsilateral hypacusis was described. Since the first description in 1912, only a few cases of this crossed brainstem syndrome were published so far. Pontine infarction and bleedings were the reported causes of the syndrome. Here we report a 44-year-old man with the classical Gasperini syndrome due to pontine demyelination in multiple sclerosis. The clinical findings were correlated with changes on MRI. The present case shows that classical crossed brainstem syndromes are topological terms not invariably associated with brainstem ischemia in particular vascular areas and may contribute to the differential diagnosis of peripheral facial nerve palsy.
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spelling pubmed-33519732012-05-16 Gasperini syndrome as clinical manifestation of pontine demyelination Krasnianski, M Müller, T Zierz, S Winterholler, M Eur J Med Res Case Report The Gasperini syndrome is a very rare brainstem disease characterized by the typical combination of ipsilateral lesions of the cranial nerves V-VII and dissociated contralateral hemihypesthesia, whereas both contralateral and ipsilateral hypacusis was described. Since the first description in 1912, only a few cases of this crossed brainstem syndrome were published so far. Pontine infarction and bleedings were the reported causes of the syndrome. Here we report a 44-year-old man with the classical Gasperini syndrome due to pontine demyelination in multiple sclerosis. The clinical findings were correlated with changes on MRI. The present case shows that classical crossed brainstem syndromes are topological terms not invariably associated with brainstem ischemia in particular vascular areas and may contribute to the differential diagnosis of peripheral facial nerve palsy. BioMed Central 2009-09-01 /pmc/articles/PMC3351973/ /pubmed/19748860 http://dx.doi.org/10.1186/2047-783X-14-9-413 Text en Copyright ©2009 I. Holzapfel Publishers
spellingShingle Case Report
Krasnianski, M
Müller, T
Zierz, S
Winterholler, M
Gasperini syndrome as clinical manifestation of pontine demyelination
title Gasperini syndrome as clinical manifestation of pontine demyelination
title_full Gasperini syndrome as clinical manifestation of pontine demyelination
title_fullStr Gasperini syndrome as clinical manifestation of pontine demyelination
title_full_unstemmed Gasperini syndrome as clinical manifestation of pontine demyelination
title_short Gasperini syndrome as clinical manifestation of pontine demyelination
title_sort gasperini syndrome as clinical manifestation of pontine demyelination
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351973/
https://www.ncbi.nlm.nih.gov/pubmed/19748860
http://dx.doi.org/10.1186/2047-783X-14-9-413
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