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Influence of the combination and phase variation status of the haemoglobin receptors HmbR and HpuAB on meningococcal virulence
Neisseria meningitidis can utilize haem, haemoglobin and haemoglobin–haptoglobin complexes as sources of iron via two TonB-dependent phase variable haemoglobin receptors, HmbR and HpuAB. HmbR is over-represented in disease isolates, suggesting a link between haemoglobin acquisition and meningococcal...
Autores principales: | Tauseef, Isfahan, Harrison, Odile B., Wooldridge, Karl G., Feavers, Ian M., Neal, Keith R., Gray, Stephen J., Kriz, Paula, Turner, David P. J., Ala’Aldeen, Dlawer A. A., Maiden, Martin C. J., Bayliss, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352162/ https://www.ncbi.nlm.nih.gov/pubmed/21310784 http://dx.doi.org/10.1099/mic.0.046946-0 |
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