Non-coding nucleotides and amino acids near the active site regulate peptide deformylase expression and inhibitor susceptibility in Chlamydia trachomatis

Chlamydia trachomatis, an obligate intracellular bacterium, is a highly prevalent human pathogen. Hydroxamic-acid-based matrix metalloprotease inhibitors can effectively inhibit the pathogen both in vitro and in vivo, and have exhibited therapeutic potential. Here, we provide genome sequencing data...

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Detalles Bibliográficos
Autores principales: Bao, Xiaofeng, Pachikara, Niseema D., Oey, Christopher B., Balakrishnan, Amit, Westblade, Lars F., Tan, Ming, Chase, Theodore, Nickels, Bryce E., Fan, Huizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Cell and Molecular Biology of Microbes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352175/
https://www.ncbi.nlm.nih.gov/pubmed/21719536
http://dx.doi.org/10.1099/mic.0.049668-0

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