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Pathophysiology of the endothelin system - lessons from genetically manipulated animal models

Shortly after discovery of ET-1 in 1988, the entire endothelin system was characterized. The endothelin system consists of the three peptides ET-1, ET-2 and ET-3, their G-protein-coupled receptors endothelin receptor A and B (ETRA and ETRB) and the two endothelin-converting enzymes (ECE-1 and ECE-2)...

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Detalles Bibliográficos
Autores principales: von Websky, K, Heiden, S, Pfab, T, Hocher, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352198/
https://www.ncbi.nlm.nih.gov/pubmed/19258203
http://dx.doi.org/10.1186/2047-783X-14-1-1