The role of CCR5 in HCV infection

Efficient recruitment and activation of immuno-competent cells is crucial for an effective immune response to hepatitis C virus (HCV) infection. Chemokines and chemokine receptors have been shown to be critically involved in these processes. The CCR5 chemokine receptor is expressed on several cells...

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Detalles Bibliográficos
Autores principales: Coenen, Martin, Nattermann, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352223/
https://www.ncbi.nlm.nih.gov/pubmed/20452893
http://dx.doi.org/10.1186/2047-783X-15-3-97
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author Coenen, Martin
Nattermann, Jacob
author_facet Coenen, Martin
Nattermann, Jacob
author_sort Coenen, Martin
collection PubMed
description Efficient recruitment and activation of immuno-competent cells is crucial for an effective immune response to hepatitis C virus (HCV) infection. Chemokines and chemokine receptors have been shown to be critically involved in these processes. The CCR5 chemokine receptor is expressed on several cells of the immune system and has been suggested to influence the susceptibility to HCV infection as well as natural course and progression of hepatitis C. However, these reports are still controversial. This review will summarize and discuss the available data regarding the potential role of CCR5 and its ligands in hepatitis C.
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spelling pubmed-33522232012-05-16 The role of CCR5 in HCV infection Coenen, Martin Nattermann, Jacob Eur J Med Res Review Efficient recruitment and activation of immuno-competent cells is crucial for an effective immune response to hepatitis C virus (HCV) infection. Chemokines and chemokine receptors have been shown to be critically involved in these processes. The CCR5 chemokine receptor is expressed on several cells of the immune system and has been suggested to influence the susceptibility to HCV infection as well as natural course and progression of hepatitis C. However, these reports are still controversial. This review will summarize and discuss the available data regarding the potential role of CCR5 and its ligands in hepatitis C. BioMed Central 2010-03-30 /pmc/articles/PMC3352223/ /pubmed/20452893 http://dx.doi.org/10.1186/2047-783X-15-3-97 Text en Copyright ©2010 I. Holzapfel Publishers
spellingShingle Review
Coenen, Martin
Nattermann, Jacob
The role of CCR5 in HCV infection
title The role of CCR5 in HCV infection
title_full The role of CCR5 in HCV infection
title_fullStr The role of CCR5 in HCV infection
title_full_unstemmed The role of CCR5 in HCV infection
title_short The role of CCR5 in HCV infection
title_sort role of ccr5 in hcv infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352223/
https://www.ncbi.nlm.nih.gov/pubmed/20452893
http://dx.doi.org/10.1186/2047-783X-15-3-97
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