Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production

BACKGROUND: Direct allorecognition, i.e., donor lung-derived dendritic cells (DCs) stimulating recipient-derived T lymphocytes, is believed to be the key mechanism of lung allograft rejection. Myeloid (cDCs) and plasmacytoid (pDCs) are believed to have differential effects on T cell activation. Howe...

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Detalles Bibliográficos
Autores principales: Benson, Heather L, Suzuki, Hidemi, Lott, Jeremy, Fisher, Amanda Jo, Walline, Crystal, Heidler, Kathleen M, Brutkiewicz, Randy, Blum, Janice S, Wilkes, David S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3352265/
https://www.ncbi.nlm.nih.gov/pubmed/22433165
http://dx.doi.org/10.1186/1465-9921-13-25

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